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Updated: Jul 5, 2026

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Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
Published on: May 8, 2018
How soon will the patient with metastasis return for radiosurgery?
Kotaro Nakaya1, Motohiro Hayashi, Masahiro Izawa
1Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan. knakaya@nij.twmu.ac.jp
Journal of Neurosurgery
|December 1, 2006
Summary
Patients undergoing repeated stereotactic radiosurgery for brain metastases typically receive it within 6 months. Regular follow-up imaging is crucial for monitoring tumor recurrence after Gamma Knife surgery (GKS).
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Stereotactic radiosurgery is a standard treatment for brain metastases.
- Some patients require repeat treatments for new or recurrent lesions.
Purpose of the Study:
- To determine the typical time interval between repeat stereotactic radiosurgery sessions for brain metastases.
- To analyze factors influencing the timing of repeat treatments.
Main Methods:
- Retrospective review of 149 patients who underwent two or more Gamma Knife surgeries (GKS) between 1999 and 2006.
- Analysis of patient demographics, number of lesions treated, and intervals between GKS procedures.
- Median intervals were analyzed for breast cancer and non-small cell lung carcinoma patients.
Main Results:
- The median interval between repeat GKS procedures was 26 weeks for breast cancer and 23 weeks for non-small cell lung carcinoma.
- The time between treatments ranged from 3 to 179 weeks across all patients.
- Patient age and number of lesions treated were analyzed.
Conclusions:
- Follow-up imaging every 2-3 months is recommended after GKS.
- This monitoring helps detect tumor recurrence and guide decisions for repeat treatments.
