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An unusual cutaneous-polyposis syndrome stabilized with acitretin
L Schmulewitz1, N Attard, L Fearfield
1Department of Dermatology, Chelsea and Westminster Hospital NHS Foundation Trust, London SW10 9NH, UK.
The British Journal of Dermatology
|May 28, 2008
Summary
Low-dose acitretin therapy stabilized gastrointestinal lesions and reduced skin issues in a patient with an unusual enterocutaneous syndrome. This treatment offers a dual benefit for complex gastrointestinal and dermatological conditions.
Area of Science:
- Dermatology and Gastroenterology
- Pharmacology
Background:
- Enterocutaneous syndrome is a complex condition affecting both the digestive tract and skin.
- Current treatment options for this syndrome may have limited efficacy or significant side effects.
Observation:
- A patient presented with an unusual manifestation of enterocutaneous syndrome.
- The patient's condition involved both gastrointestinal lesions and significant cutaneous morbidity.
Findings:
- Long-term, low-dose acitretin treatment was administered.
- Acitretin effectively stabilized the progression of gastrointestinal lesions.
- Concurrently, acitretin treatment led to a reduction in cutaneous symptoms.
Implications:
- Low-dose acitretin may represent a viable therapeutic strategy for managing enterocutaneous syndromes.
- This approach demonstrates potential for addressing both gastrointestinal and dermatological aspects of the condition.
- Further research into acitretin's efficacy and safety in enterocutaneous syndrome is warranted.
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