Related Experiment Video
Updated: Jul 5, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Hand eczema: causes, course, and prognosis I
Niels K Veien1, Thais Hattel, Grete Laurberg
1The Dermatology Clinic, Vesterbro 99, DK-9000 Aalborg, Denmark. veien@dadlnet.dk
Contact Dermatitis
|May 28, 2008
Summary
Hand eczema often presents as a chronic condition. Irritant contact dermatitis is the most frequent cause, affecting a significant portion of patients in this study.
Area of Science:
- Dermatology
- Epidemiology
Background:
- Hand eczema is a prevalent skin condition with a frequently prolonged course.
- The long-term prognosis and detailed characteristics of hand eczema require further elucidation.
Purpose of the Study:
- To comprehensively characterize a cohort of hand eczema patients.
- To investigate the etiological factors, morphological presentations, and disease dynamics in hand eczema.
Main Methods:
- Prospective study of 522 consecutive hand eczema patients over one year.
- Patch testing was performed on 81% of patients, with most others having prior testing.
- Data collected included disease severity, duration, etiology, and potential occupational links.
Main Results:
- The majority of patients experienced moderate to severe dermatitis.
- A significant percentage (23%) had disease duration exceeding 10 years.
- Irritant contact dermatitis was the most common diagnosis (33%), followed by allergic contact dermatitis and atopic dermatitis. Occupational factors were identified in a substantial proportion of cases.
Conclusions:
- Hand eczema is frequently a long-standing dermatosis.
- Irritant contact dermatitis is the predominant etiological factor identified in this patient cohort.
- Understanding these factors is crucial for effective management and prognosis.
Related Concept Videos
01:27Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
01:23Hand hygiene
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
01:19Handwashing II: Pre-procedure and Initial Procedure Steps
The pre-procedure steps of handwashing include removing jewelry and rolling up sleeves. However, many organizations allow staff to wear wedding rings.
The hand washing procedure itself includes the following steps. First, cover cuts, if any, on hands with a waterproof dressing. Cuts and abrasions can become contaminated with bacteria hindering the ability to clean the area thoroughly. In addition, repeated hand washing can worsen an injury. The nails must be short and clean, without nail paint...
The hand washing procedure itself includes the following steps. First, cover cuts, if any, on hands with a waterproof dressing. Cuts and abrasions can become contaminated with bacteria hindering the ability to clean the area thoroughly. In addition, repeated hand washing can worsen an injury. The nails must be short and clean, without nail paint...
01:23Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
01:23Chronic Obstructive Pulmonary Disease I: Introduction
Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
01:19Clinical Applications of Epidermal Stem Cells
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...