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Updated: Jul 5, 2026
12:27
Noninvasive In Vivo Small Animal MRI and MRS: Basic Experimental Procedures
Published on: October 20, 2009
[Small animal MRI: clinical MRI as an interface to basic biomedical research]
J G Pinkernelle1, L Stelter, B Hamm
1Institut für Radiologie, Charité Universitätsmedizin Berlin, Berlin. jens.pinkernelle@charite.de
Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|May 28, 2008
Summary
Clinical magnetic resonance imaging (MRI) scanners are effective for small animal imaging in biomedical research. They offer accessible, cost-effective, high-resolution imaging with translational value.
Area of Science:
- Biomedical imaging
- Medical physics
Context:
- Increasing demand for high-resolution small animal MRI in biomedical research.
- Dedicated ultra-high field MRI scanners (4.7-7.0 T) offer optimal performance.
- Clinical MRI scanners (up to 3.0 T) are frequently utilized for small animal imaging.
Purpose:
- To evaluate the utility of clinical MRI scanners for small animal imaging.
- To highlight the advantages of using clinical MRI systems for research.
Summary:
- High-resolution radiofrequency (RF) coils, including single-loop designs, enable excellent tissue contrast in small animal MRI using clinical scanners.
- Custom RF coils and gradient inserts can be employed in clinical scanners for enhanced performance.
- Specialized MRI-compatible devices for ECG and respiration monitoring reduce motion artifacts.
Impact:
- Clinical MRI systems provide a cost-effective, readily available solution for small animal imaging.
- The use of clinical scanners offers good imaging performance and translational relevance for research findings.
- Facilitates widespread adoption of advanced imaging techniques in preclinical research.
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