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Updated: Jul 5, 2026

Rapid Collection of Floral Fragrance Volatiles using a Headspace Volatile Collection Technique for GC-MS Thermal Desorption Sampling
Published on: December 10, 2019
Interaction of Fragrance Materials With 2-Hydroxypropyl-beta-Cyclodextrin by Static and Dynamic Head-space Methods
1Faculty of Pharmaceutical Science, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142, Japan.
Abstract:
The stability constants for the inclusion of fragrance materials with 2-hydroxypropyl-beta-cyclodextrin (2HP-beta-C yD) in aqueous solution have been determined by the static head-space method. The 1:1 stability constants obtained by this method were in reasonable agreement with the corresponding values in the literature. In addition, the release profiles of fragrance materials from 2HP-beta-CyD aqueous solution were investigated using the dynamic head-space method. It was found that the suppression of the fragrance materials release was dependent on their stability constants.
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