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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Radiosurgery with a linear accelerator in cerebral arteriovenous malformations
Sérgio Carlos Barros Esteves1, Wladimir Nadalin, Ronie Leo Piske
1Hospital Beneficência Portuguesa de São Paulo, São Paulo, SP. estevesrt@uol.com.br
Revista Da Associacao Medica Brasileira (1992)
|May 29, 2008
Summary
Linear accelerator radiosurgery effectively treats arteriovenous malformations, offering an alternative for complex cases. No statistically significant factors were found to correlate with successful obliteration or treatment complications.
Area of Science:
- Neurosurgery
- Radiation Oncology
Background:
- Arteriovenous malformations (AVMs) present significant neurological risks.
- Radiosurgery is explored as a treatment option for AVMs, particularly for those in eloquent areas or with contraindications to other therapies.
Purpose of the Study:
- To evaluate the efficacy and complication rates of linear accelerator radiosurgery in treating brain arteriovenous malformations.
- To identify factors influencing successful obliteration and treatment-related complications.
Main Methods:
- A retrospective analysis of 61 patients with AVMs treated with linear accelerator radiosurgery between 1993 and 1996.
- Patient demographics, AVM characteristics (Spetzler grade, angioarchitecture), and treatment parameters (dose) were recorded.
- Angiographic follow-up was used to assess obliteration rates.
Main Results:
- Complete obliteration was achieved in 72% of patients with conclusive follow-up angiography.
- Treatment failure occurred in 7 patients, with 4 undergoing a second radiosurgery.
- No statistically significant correlation was found between analyzed variables (e.g., AVM volume, dose) and occlusion rates or complications.
Conclusions:
- Linear accelerator radiosurgery is an effective treatment for arteriovenous malformations.
- It serves as a viable alternative for patients with contraindications to other treatments or AVMs in critical brain regions.
- No statistically significant correlation was observed between occlusion and treatment complications among the studied variables.
