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Updated: Jul 4, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Topical therapy for the management of childhood psoriasis: part I
1Department of Dermatology, University of California, San Francisco, CA, USA.
Insights
Psoriasis significantly impacts quality of life, with most cases managed by topical treatments. Severe pediatric psoriasis may require systemic therapy, with treatment choices balancing efficacy, safety, and patient factors.
Area of Science:
- Dermatology
- Pediatric Medicine
Background:
- Psoriasis is a chronic skin condition with significant physical, emotional, and social impacts.
- While most cases are mild and treated topically, severe forms, especially in children, necessitate systemic therapies.
Purpose of the Study:
- To review topical agents for psoriasis management.
- To discuss the effectiveness, side effects, and clinical applications of topical psoriasis treatments, particularly in pediatric cases.
Main Methods:
- Review of current literature on topical psoriasis treatments.
- Analysis of treatment considerations including disease severity, comorbidities, and patient-specific factors.
Main Results:
- Topical medications are effective for mild psoriasis.
- Treatment decisions for severe psoriasis involve a comprehensive assessment of disease characteristics and patient-related factors.
Conclusions:
- Topical agents form the cornerstone of mild psoriasis management.
- Part I of this series focuses on topical treatments, laying the groundwork for understanding more complex therapeutic options.
Abstract:
Psoriasis represents a potentially life-altering disease that can profoundly impact physical, emotional and social functioning, and overall quality of life. The majority of cases are mild and managed adequately with topical medications. A minor subset of children present with severe, rapidly evolving disease that requires systemic therapy. The choice of treatment in children, as in adults, is determined by disease acuity, morphology, distribution, severity and the presence of comorbidities such as psoriatic arthropathy. Practical considerations such as ease of use, patient acceptability, accessibility, risk to benefit ratio, cost and individual perceptions of disease and quality of life are factored into treatment decisions. Part I of this 2-part series will focus on topical agents, their varying degrees of effectiveness, potential side-effects and applications in clinical practice.
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