Systemic and light therapies for the management of childhood psoriasis: part II

K M Cordoro1

  • 1Department of Dermatology, University of California, San Francisco, CA, USA.

Skin Therapy Letter
|July 24, 2008
PubMed

Insights

Psoriasis treatment in children depends on severity. While most cases respond to topical treatments, severe pediatric psoriasis requires advanced systemic and phototherapy, though these are not well-studied for this age group.

Area of Science:

  • Pediatric Dermatology
  • Dermatological Therapeutics

Background:

  • Psoriasis treatment selection in children mirrors adult approaches, considering disease factors like acuity, morphology, distribution, severity, and comorbidities such as psoriatic arthropathy.
  • Most pediatric psoriasis cases are mild and effectively managed with topical medications.

Purpose of the Study:

  • To provide an overview of advanced systemic and phototherapy options for pediatric psoriasis.
  • To discuss the effectiveness, potential side-effects, and clinical applications of these advanced treatments in children.

Main Methods:

  • Review of systemic and light therapies for pediatric psoriasis.
  • Analysis of existing data on effectiveness and side-effects.

Main Results:

  • Mild pediatric psoriasis typically responds well to topical treatments.
  • A small subset of children experiences severe, rapidly progressing psoriasis necessitating advanced interventions.
  • Systemic and phototherapy for pediatric psoriasis are challenging due to limited research and lack of specific approvals.

Conclusions:

  • Topical treatments are the mainstay for mild pediatric psoriasis.
  • Advanced therapies like systemic agents and phototherapy require careful consideration due to limited evidence and potential risks in children.
  • Further research is crucial to establish evidence-based guidelines for advanced psoriasis treatment in pediatric populations.

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