[Adult depressive disorder: clinical aspects, nosography and psychiatrics comorbidity]

Depressed mood and anhedonia are the main symptoms of depressive disorder. With other symptoms, it is responsible for a real break with premorbid patient's way of life. Several clinicals forms, caracterised by melancholia intensity, psychotic symptoms and cognitive troubles, must be identified to adapt treatment and to prevent patients from particular risks. The short and middle term prognosis is linked to the suicidal risk and the socioprofessionnal and familial consequences. Long term risk is the disease chronicisation, recurrence and bipolarity. The existence of other psychiatric comorbidity, such as alcoholism, personality disorder, anxiety disorder, is frequent and must be envisaged, despite the difficulty linked with symptoms intrication.