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Updated: Jul 4, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
[Depression and personality disorders]
1Université Paris V-René Descartes, clinique des maladies mentales et de l'encéphale, hôpital Sainte-Anne, 75674 Paris Cedex 14. jd.guelfi@ch-sainte-anne.fr
Abstract:
The association between depressive disorders and personality disorders is frequent. They need to be acknowledged in general practice for a better treatment (therapeutic alliance, compliance). Twenty to 50% of psychiatric inpatients and 50 to 85% of outpatients with a major depressive episode also have an associated personality disorder, most frequently borderline, avoidant, dependent or obsessive. These associations, as well as the so-called depressive personality disorder, have many implications for other persistant mood disorders such as dysthymic disorders. This article discusses the therapeutic options for an optimal treatment of these disorders.
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