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Vertebral osteomyelitis and native valve endocarditis due to Staphylococcus simulans: a case report
Natalia Vallianou1, Angelos Evangelopoulos, Polyxeni Makri
1Department of Internal Medicine, Polykliniki General Hospital, Athens, Greece. natalia.vallianou@hotmail.com
Background:
Staphylococcus simulans is a common animal pathogen that occasionally can colonize human skin. Unlike other coagulase-negative staphylococci, S. simulans tends to cause more severe infections that resemble those caused by S. aureus. We present a case of vertebral osteomyelitis and endocarditis due to S. simulans. To the best of our knowledge, this is the first report of vertebral osteomyelitis associated with native valve endocarditis rather than orthopedic surgery.
Case Presentation:
A 46-year-old male butcher was admitted to the hospital with a 4-week history of high fever with profound sweating. He reported weakness in his legs and low back pain that compromised his walking ability. Blood cultures yielded Gram-positive cocci on Gram stain. These cocci were identified to the species level as S. simulans, a coagulase-negative staphylococcus. The patient was treated with antibiotics, which were discontinued after 6 months.
Conclusion:
This case illustrates the importance of identifying coagulase-negative staphylococci to the species level. Accurate identification of S. simulans would further help investigations defining its pathogenic role in human infections.
Insights
Staphylococcus simulans, an animal pathogen, can cause severe human infections like osteomyelitis and endocarditis. This case highlights the importance of species-level identification for understanding its pathogenic role.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Clinical Case Reports
Background:
- Staphylococcus simulans is an animal pathogen that can colonize human skin.
- It may cause severe infections, mimicking those of Staphylococcus aureus.
- This report details a rare case of vertebral osteomyelitis and native valve endocarditis caused by S. simulans.
Purpose of the Study:
- To report a unique case of severe human infection caused by Staphylococcus simulans.
- To emphasize the significance of accurate species-level identification of coagulase-negative staphylococci.
- To contribute to understanding the pathogenic potential of S. simulans in humans.
Main Methods:
- A case of a 46-year-old male butcher with symptoms of infection was investigated.
- Blood cultures were performed, and Gram-positive cocci were identified as S. simulans.
- The patient received a 6-month course of antibiotic treatment.
Main Results:
- The patient presented with vertebral osteomyelitis and native valve endocarditis.
- S. simulans was identified as the causative agent.
- Successful treatment with antibiotics was achieved after 6 months.
Conclusions:
- Accurate species-level identification of coagulase-negative staphylococci is crucial.
- This case underscores the potential severity of S. simulans infections in humans.
- Further research is needed to define the pathogenic role of S. simulans.
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