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Updated: Jul 4, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Emerging applications for transseptal left heart catheterization old techniques for new procedures
Vasilis C Babaliaros1, Jacob T Green, Stamatios Lerakis
1Andreas Gruentzig Cardiovascular Center, Emory University Hospital, Atlanta, Georgia 30322, USA. Vasilis.babaliaros@emoryhealthcare.org
Transseptal catheterization, a technique for accessing the left atrium, is seeing renewed interest for new cardiac procedures. Invasive cardiologists must relearn this essential skill and utilize advanced imaging for guidance.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Cardiac Catheterization
Background:
- Transseptal (TS) catheterization, introduced in 1959, was initially used for direct left atrial (LA) pressure measurement.
- Its diagnostic use has declined, replaced by indirect methods like the Swan-Ganz catheter, leading to a loss of expertise.
- However, TS puncture remains crucial for specific interventions like balloon valvuloplasty and arrhythmia ablation.
Purpose of the Study:
- To highlight the resurgence of interest in the transseptal catheterization technique.
- To emphasize the need for invasive cardiologists to update their skills in TS puncture.
- To underscore the importance of advanced imaging in guiding modern TS procedures.
Main Methods:
- Review of the historical and current applications of transseptal catheterization.
- Discussion of emerging therapeutic procedures necessitating TS access.
- Emphasis on the role of contemporary ultrasound imaging and devices in TS guidance.
Main Results:
- Transseptal catheterization is experiencing a revival due to novel structural heart disease interventions and atrial fibrillation ablation.
- Expertise in the traditional TS puncture technique has diminished in many centers.
- Newer TS devices and advanced ultrasound guidance are becoming integral to the procedure.
Conclusions:
- Invasive cardiologists require re-familiarization with transseptal catheterization techniques.
- Mastery of TS puncture is essential for upcoming therapeutic cardiac interventions.
- Integration of advanced imaging and updated devices is critical for successful TS procedures.
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