Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Intestinal Obstruction I: Introduction

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...

Intestinal Obstruction II: Pathophysiology

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

Assessment of the Rectum and Anus

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...

Diverticular Disease of the Colon

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dietary Tryptophan Supplementation Attenuates Lipopolysaccharide-Induced Acute Lung Injury in a Murine Model of Colitis.

Nutrients·2026

Same author

Comparison of transoral and bilateral axillo-breast approach endoscopic thyroidectomy: multicentre study.

BJS open·2026

Same author

From adipokine to integrator: longitudinal galectin-1 changes mirror glycemic, hepatic, renal, and lipid remodeling after bariatric surgery.

Nutrition & diabetes·2026

Same author

Dual-wavelength cylindrical vector beams in Nd:GdVO<sub>4</sub> lasers with identical and orthogonal polarizations.

Optics letters·2026

Same author

Dysregulated Epithelial Shedding Promotes Early Intestinal Hyperpermeability Following Major Burn Injury.

Journal of burn care & research : official publication of the American Burn Association·2026

Same author

Dose-response effect of statins on colorectal cancer risk in IBD: a nationwide cohort study.

BMC cancer·2026

Search research articles

Related Experiment Video

Updated: Jul 4, 2026

A Mouse Model of Intestinal Partial Obstruction

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

Multiple small-bowel intussusceptions caused by metastatic malignant melanoma.

Yan-Jiun Huang¹, Ming-Hsun Wu, Ming-Tsan Lin

¹Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.

American Journal of Surgery

|June 3, 2008

Summary

Small bowel intussusception caused by metastatic melanoma tumors requires surgical resection. Complete removal of visible tumors offers the best chance for long-term survival, though outcomes remain poor.

More Related Videos

The Role of Anatomical Dissection in Defining Colic and Small Bowel Artery Lymphovascular Bundles in the D3 Volume of Small and Large Bowel Mesentery

The Role of Anatomical Dissection in Defining Colic and Small Bowel Artery Lymphovascular Bundles in the D3 Volume of Small and Large Bowel Mesentery

Published on: August 1, 2025

Related Experiment Videos

Last Updated: Jul 4, 2026

A Mouse Model of Intestinal Partial Obstruction

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

The Role of Anatomical Dissection in Defining Colic and Small Bowel Artery Lymphovascular Bundles in the D3 Volume of Small and Large Bowel Mesentery

The Role of Anatomical Dissection in Defining Colic and Small Bowel Artery Lymphovascular Bundles in the D3 Volume of Small and Large Bowel Mesentery

Published on: August 1, 2025

Area of Science:

Gastroenterology
Surgical Oncology
Pathology

Background:

Small bowel intussusception is a rare condition in adults.
Intraluminal metastatic tumors are an uncommon cause of adult intussusception.
Melanoma metastasis to the small bowel can present as intussusception.

Observation:

During surgery, intussusception of the small bowel was identified.
Multiple intraluminal metastatic tumors were present within the affected segment.
Histologic examination confirmed metastatic melanoma as the cause.

Findings:

Complete surgical resection of macroscopic tumors was performed.
Metastatic melanoma was the definitive histologic diagnosis.
The patient's long-term survival prognosis is poor.

Implications:

Complete surgical resection of visible tumors is the primary treatment for metastatic melanoma causing intussusception.
Further research is needed to improve long-term survival rates for such cases.
Multidisciplinary approaches may be beneficial for managing metastatic melanoma in the gastrointestinal tract.