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Related Experiment Video

Updated: Jul 4, 2026

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

Published on: April 16, 2019

Lymphatics in lung disease.

Souheil El-Chemaly¹, Stewart J Levine, Joel Moss

¹Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg. 10, Rm 6D03, MSC 1590, Bethesda, MD 20892-1590, USA.

Annals of the New York Academy of Sciences

|June 4, 2008

Summary

The lymphatic system is crucial for lung health and disease. Understanding lung lymphatics aids in developing new treatments for conditions like asthma and cancer.

Area of Science:

Pulmonary biology and disease pathology.

Background:

The lymphatic circulation plays a critical role in lung biology.
Animal models demonstrate its involvement in lung cancer and asthma.

Purpose of the Study:

To elucidate the function of lung lymphatics in disease pathogenesis.
To identify novel therapeutic targets for lung diseases.

Main Methods:

Utilized animal models to study lung lymphatic function.
Investigated molecular controls of lymphangiogenesis in lung development.

Main Results:

Established the role of lymphatic circulation in neoplastic and inflammatory lung diseases.
Advanced understanding of lymphangiogenesis in normal lung development.

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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Related Experiment Videos

Last Updated: Jul 4, 2026

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

Published on: April 16, 2019

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Conclusions:

Understanding lung lymphatics is key to disease pathogenesis.
Further research may lead to new therapeutic strategies for human lung diseases.