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Updated: Jul 4, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Change of acoustic parameters before and after treatment in laryngopharyngeal reflux patients
bBong Joon Jin1, Yong Seop Lee, Seung Won Jeong
1Department of Otolaryngology-Head and Neck Surgery, School of Medicne, Hangyang University, Seoul, Korea.
Objectives:
To evaluate the usefulness of acoustic parameters as an indicator of laryngopharyngeal reflux (LPR) treatment efficacy.
Study Design:
A prospective case series analysis.
Materials And Methods:
From January to September 2005, we prospectively analyzed 40 patients who were diagnosed with laryngopharyngeal reflux by 24-hour ambulatory double-probe pH monitoring. Laryngopharyngeal reflux patients were treated medically and voice analysis was conducted three times: before treatment, 1 to 2 months after treatment, and 3 to 4 months after treatment. Jitter, shimmer, and harmonic-to-noise ratio (HNR) were analyzed as the acoustic parameters. Pre- and posttreatment reflux symptom index and reflux finding score were documented.
Results:
Jitter, shimmer, and HNR had improved significantly at 1 to 2 months after treatment and were maintained at 3 to 4 months after treatment. Jitter was significantly correlated with reflux symptom index.
Conclusion:
Acoustic parameters can be used as indicators of treatment efficacy for laryngopharyngeal reflux disease.
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