[Vogt Koyanagi Harada syndrome]

Area of Science:

• Ophthalmology
• Immunology
• Neurology

Background:

• Vogt Koyanagi Harada syndrome is a rare systemic inflammatory disorder affecting the eyes, central nervous system, and skin.
• It typically presents as a bilateral granulomatous panuveitis, often leading to exudative retinal detachment.

Observation:

• Two cases of female patients presenting with visual disturbances and migraine were diagnosed with exudative, bilateral retinal detachment.
• Both patients received immunosuppressive therapy, including steroids and cyclosporine-A in one case.

Findings:

• Following treatment, both patients experienced significant visual recovery.
• Case 1 achieved 10/10 vision in the right eye and 9/10 in the left eye.
• Case 2 achieved 9/10 vision in the right eye and 8/10 in the left eye.

Implications:

• Prompt diagnosis and early immunosuppressive treatment are crucial for favorable visual outcomes in Vogt Koyanagi Harada syndrome.
• The findings underscore the importance of suspecting this condition in patients with bilateral retinal detachment and systemic symptoms.
• This highlights the potential for vision restoration in patients with this challenging condition.