Related Experiment Video
Updated: Jul 27, 2026

A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis
Published on: March 24, 2017
[New approaches to the treatment of mycobacterioses of the lungs]
Abstract:
The paper deals with improvement of pulmonary mycobacterioses treatment. In the preliminary experiments with the use of an experimental model, 32 regimens of M. avium mycobacteriosis treatment were tested on 872 white mice and the most efficient one was chosen, which comprised a combination of kanamycin-ethambutol-thionamide coupled with sulfadimethoxine and thymalin courses. The clinical course and results of treatment of 43 patients (23 of the main and 20 of the control group) with fibro-cavernous pulmonary mycobacteriosis were studied. Employment of the new treatment regimen significantly enhanced its efficiency--the incidence of bacillary excretion cessation increased from 30 to 82.6%.
Related Concept Videos
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Atypical Pneumonia

