[The use of demineralized bone allograft with given properties for filling in jaw defects]

The course of reparative regeneration was studied in 112 rabbits 3-4 kg b. w., in whom perforating defects 10 mm in diameter were filled with ground allobone and mineral-free allobone preserved in 0.25 percent formalin or mineral-free allobone impregnated with antiseptic solution. Histologic, histochemical, and morphometric investigations have revealed that the latter variant of defect filling lead to the most active graft restructuring with development of lamellar bone tissue. No cartilagenous stage was recorded over the course of bone tissue development in any case. Preservation of mineral-free bone in 0.25 percent formalin solution reduced its osteogenic abilities.