Related Experiment Video
Updated: Jul 4, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Published on: July 20, 2022
Retrospective analysis of catheter recirculation in prevalent dialysis patients
Shahab Moossavi1, Tushar J Vachharajani, Jean Jordan
1Wake Forest University Outpatient Dialysis Centers, Wake Forset University School of Medicine, Winston-Salem, North Carolina 27157-1053, USA.
Insights
Catheter recirculation (CR) in hemodialysis patients is not significantly influenced by catheter type, brand, or duration of use. This finding suggests CR is largely independent of these common factors in prevalent hemodialysis cases.
Area of Science:
- Nephrology
- Vascular Access
- Dialysis Technology
Background:
- Catheter recirculation (CR) compromises hemodialysis adequacy by allowing premature blood return.
- Understanding factors influencing CR is crucial for optimizing dialysis treatment efficacy.
Purpose of the Study:
- To investigate the relationship between central venous catheter (CVC) characteristics and the degree of CR in prevalent hemodialysis patients.
- To identify key determinants of CR to improve dialysis access outcomes.
Main Methods:
- Retrospective analysis of 165 hemodialysis patients using CVCs at Wake Forest University Outpatient Dialysis Facilities.
- CR was measured using ultrasound dilution technique and correlated with catheter type, brand, placement site, length, and duration of use.
Main Results:
- No significant correlation was found between CR and catheter brand, type (symmetric, split, step-tip), or placement site in tunneled catheters (p=0.80).
- CR was not associated with time on dialysis (p=0.66) or time on the current catheter (p=0.48).
- Temporary catheters showed higher CR (23.0 +/- 8.2%), but this was borderline significant (p=0.052) when included.
Conclusions:
- Central venous catheter recirculation in hemodialysis appears independent of catheter brand, type, and duration of use for tunneled catheters.
- Optimizing dialysis adequacy may require focusing on factors beyond CVC characteristics, such as proper catheter placement and patient-specific hemodynamics.
Abstract:
Catheter recirculation (CR) occurs when blood returning from the venous limb of the catheter re-enters the arterial limb of the catheter without passage through the circulation. Adequacy of dialysis is influenced by the degree of access recirculation. In this study we evaluate factors influencing the degree of dialysis central venous catheter (CVC) recirculation in prevalent hemodialysis patients. This is a retrospective study of all patients undergoing hemodialysis via a catheter at the Wake Forest University Outpatient Dialysis Facilities from September 1, 2006 to May 15, 2007. CR was correlated to catheter type, catheter brand, site of placement, catheter length, time on dialysis, time on the current catheter, and was measured via ultrasound dilution technique. A total of 165 catheters were identified. Seventy-one catheters were in the right internal jugular position, 43 in the left internal jugular position, 13 in the right subclavian, one in the left subclavian, eight in the right femoral, two in the left femoral, and four in the trans-lumber position. CR was 6.3 +/- 7.5% in symmetric tip catheters (n = 14), 6.0 +/- 8.3% in split-tip catheters (n = 102), 8.4 +/- 11.7% in step-tip catheters (n = 10), and 23.0 +/- 8.2% in temporary catheters (n = 3), respectively. These results are borderline significant if temporary catheters are included (p = 0.052); however, the overall p-value is only 0.80 for tunneled dialysis catheters. There was no correlation between CR and time on dialysis (p = 0.66) or time on the current catheter (p = 0.48). The current study suggests that the CVC recirculation is independent of catheter brand, type, time on dialysis, or time on current catheter.
Related Concept Videos
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
Continuous Renal Replacement Therapy
Hemodialysis II: Procedure and Complications
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Hemodialysis III: Nursing Management
Cardiac Catheterization I: Pre-Procedure Overview
