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Updated: Jul 4, 2026

Fluorescence-Activated Cell Sorting for the Isolation of Scleractinian Cell Populations
Published on: May 31, 2020
Cembrane diterpenoids from the taiwanese soft coral Sarcophyton stolidotum
Yuan-Bin Cheng1, Ya-Ching Shen, Yao-Haur Kuo
1Institute of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan, Republic of China.
Abstract:
Investigation of an EtOAc-soluble extract of the soft coral Sarcophyton stolidotum resulted in the isolation of seven new 14-membered carbocyclic cembranes, sarcostolides A-G (1-7), together with two known cembrane diterpenes, isosarcophytoxide and isosarcophine. The structural elucidation of these metabolites was determined on the basis of spectroscopic analyses, particularly 2D NMR techniques. Sarcostolide E (5) exhibited weak to moderate cytotoxic activity against human WiDr and Daoy tumor cell lines. A biogenetic pathway and relationship for compounds 1-7 was also proposed.
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