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Updated: Jul 4, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Endothelial Lipase: a key player in HDL metabolism modulates inflammation and atherosclerotic risk
Pascual DeSantis1, Trey Coleman, Stephan Schiekofer
1Washington University in St. Louis, Department of Internal Medicine, St. Louis, MO 63110, USA.
Abstract:
Endothelial Lipase (EL) is a newly identified member of the triacylglycerol lipase family. Recent studies suggested that EL may be an important determinant of HDL-metabolism and inflammation acting at the level of the vessel wall. The aim of this review is to summarize important facts derived from experimental approaches and from epidemiologic human studies to provide a comprehensive view on the role of EL in inflammation and atherogenesis as well as target for potential pharmaceutical interventions.
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