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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

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Published on: February 6, 2019

Proton beam therapy interference with implanted cardiac pacemakers.

Yoshiko Oshiro¹, Shinji Sugahara, Mio Noma

¹Department of Radiation Oncology, University of Tsukuba, Ibaraki, Japan.

International Journal of Radiation Oncology, Biology, Physics

|June 10, 2008

Summary

This summary is machine-generated.

Proton beam therapy (PBT) may affect cardiac pacemaker function, causing asymptomatic heart rate changes. Continuous electrocardiogram monitoring during PBT is recommended for patients with pacemakers.

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Area of Science:

Radiation oncology
Cardiology
Medical physics

Background:

Proton beam therapy (PBT) is an advanced radiation technique.
Implanted cardiac pacemakers are common in patients requiring radiation treatment.
The potential interaction between PBT and pacemaker function requires investigation.

Purpose of the Study:

To evaluate the impact of PBT on the function of implanted cardiac pacemakers.
To assess the safety and efficacy of PBT in patients with cardiac pacemakers.

Main Methods:

A phantom study was conducted to confirm PBT safety.
Eight patients with implanted pacemakers received PBT (33-77 GyE total dose).
Pacemaker function was monitored via electrocardiogram during and after PBT sessions.

Main Results:

The phantom study indicated no adverse effects from neutron scatter on pacemaker generators.
Two patients (2.4%) experienced asymptomatic heart rate changes during PBT.
No significant pacemaker malfunctions requiring intervention were observed.

Conclusions:

PBT can potentially cause pacemaker malfunctions, including alterations in pulse rate and pattern.
Electrocardiogram monitoring during PBT is crucial for patients with cardiac pacemakers.
PBT can be safely administered to patients with pacemakers, provided appropriate monitoring is in place.