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[Endoscopic management of severe pancreatic and biliary diseases in children]
G Lamblin1, A Desjeux, J-C Grimaud
1Service de gastroentérologie, hôpital Nord, chemin des Bourrely, Marseille cedex 20, France.
Insights
Endoscopic therapy for pancreatic and biliary diseases is safe and effective in children, mirroring adult outcomes. This approach successfully treated conditions like choledocholithiasis and pseudocysts in pediatric patients.
Area of Science:
- Pediatric Gastroenterology
- Minimally Invasive Surgery
- Endoscopic Procedures
Background:
- Endoscopic management of pancreatic pseudocysts and choledochal lithiasis is standard for adults.
- Pediatric endoscopic treatment presents unique technical challenges, limiting its widespread application.
- This study evaluates the feasibility and outcomes of endoscopic interventions for pancreatic and biliary diseases in children.
Observation:
- Seven pediatric patients (2 months to 12 years) underwent endoscopic treatment for pancreatic and biliary conditions.
- Conditions included choledochal lithiasis, post-traumatic pancreatic pseudocysts, chronic pancreatitis, and biliary leakage.
- Procedures utilized standard duodenoscopes, specialized techniques like "rendez-vous" for infants, and stent placements.
Findings:
- All seven children achieved symptom resolution without procedural complications.
- Successful endoscopic treatments included stone extraction, pseudocyst management, sphincterotomy, and biliary stenting.
- Median follow-up of 11 months demonstrated sustained positive outcomes.
Implications:
- Pediatric endoscopic retrograde cholangiopancreatography (ERCP) and related interventions are viable and safe.
- Endoscopic therapy offers comparable results to adult treatment paradigms for pediatric pancreatic and biliary diseases.
- This validates endoscopic procedures as a crucial treatment modality in pediatric gastroenterology.
Abstract:
Endoscopic treatment of pancreatic pseudocysts and choledocal lithiasis is a first-line treatment in adults. Nevertheless, due to technical difficulties such a management is not always feasible in children. This series reports our results in the management of pancreatic and biliary diseases in children. Seven children, two months to 12 years old, underwent endoscopic management of pancreatic and biliary diseases. Two of them had choledocal lithiasis with jaundice or acute pancreatitis, two had pancreatic pseudocyst due to abdominal traumatism, two had chronic pancreatitis with a communicating pseudocyst in one case, and one had a biliary leakage after traumatism. All the endoscopic treatments were performed under general anesthesia. In six cases, the duodenoscope was a regular one with a large operating channel (Olympus TJF 160; Japan) employed for children aged 33 months to 12 years. In the case of the two months child, a "rendez-vous" technique was performed with a percutaneous approach of the common bile duct followed by an endoscopic sphincteroclasy using an axial endoscope allowing the extraction of a choledocal stone. In two cases, post-traumatic pancreatic pseudocysts (eight and 12 year-old children) were managed with the transgastric insertion of two double pig-tail stents. In two cases, children with chronic pancreatitis (38 months and 12 years old) were managed with pancreatic sphincterotomy. Biliary leakage in an 11-year-old child was managed with biliary sphincterotomy and stenting. All the children became symptom-free without any procedural complications with an 11 months median follow-up. Endoscopic treatment of pancreatic and biliary diseases is possible in children like in adults with the same procedures and results.
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