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Related Concept Videos

Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Therapeutic Index01:13

Therapeutic Index

The therapeutic index of a drug is a key parameter in pharmacology that quantifies the relative safety of a drug by calculating the ratio between the dose that causes toxicity in half the population (50%) to the dose that proves to be effective for half the population (50%). It provides a spectrum of doses for a particular drug ranging from effective to potentially toxic. To illustrate, consider an anticoagulant agent like warfarin. It possesses a narrow window within its therapeutic index to...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...

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Updated: Jul 4, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

[Therapeutic algorithm].

Koji Abe1

  • 1Department of Neurology and Neuroscience, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|June 11, 2008
PubMed
Summary
This summary is machine-generated.

Treatment for myasthenia gravis (MG) and myasthenic syndrome varies by patient age and specific condition. Adults with MG typically undergo thymectomy, while children

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Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

Area of Science:

  • Neurology
  • Immunology
  • Oncology

Context:

  • Myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are rare autoimmune disorders affecting neuromuscular transmission.
  • These conditions present distinct diagnostic and therapeutic challenges.
  • Understanding optimal treatment pathways is crucial for patient outcomes.

Purpose:

  • To outline current therapeutic algorithms for myasthenia gravis and Lambert-Eaton myasthenic syndrome.
  • To differentiate treatment strategies based on patient demographics and underlying causes.
  • To provide a clinical guideline for managing these complex neuromuscular disorders.

Summary:

  • For adult myasthenia gravis patients, thymectomy is the primary recommended therapy.
  • Pediatric myasthenia gravis treatment is individualized, considering age at onset and may involve drug therapy or surgery.
  • Lambert-Eaton myasthenic syndrome management prioritizes treating associated malignancies, particularly lung cancer in males, followed by pharmacotherapy.

Impact:

  • This guidance can help clinicians optimize treatment selection for MG and LEMS patients.
  • Standardizing therapeutic approaches may improve patient prognosis and quality of life.
  • Highlights the importance of a multidisciplinary approach in managing rare neuromuscular junction disorders.