Related Experiment Video
Updated: Jul 4, 2026

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
Published on: May 15, 2014
Medical statistics and hospital medicine: the case of the smallpox vaccination
1Department of History, University of Rhode Island.
Abstract:
Between 1799 and 1806, trials of vaccination to determine its safety and efficacy were undertaken in hospitals in London, Paris, Vienna, and Boston. These trials were among the first instances of formal hospital evaluations of a medical procedure and signal a growing acceptance of a relatively new approach to medical practice. These early evaluations of smallpox vaccination also relied on descriptive and quantitative accounts, as well as probabilistic analyses, and thus occupy a significant, yet hitherto unexamined, place in the history of medical statistics.
More Related Videos
Related Concept Videos
Smallpox
Vaccinations
Introduction to Epidemiology
Statistical Methods for Analyzing Epidemiological Data
Principles of Disease Surveillance
Steps in Outbreak Investigation

