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Related Experiment Video

Updated: Jul 4, 2026

Modeling Cataract Surgery in Mice

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

[Systane and cataract surgery].

C Stefan¹, Diana Melinte Dumitrica

¹Central Clinical Military Hospital, Bucharest, Romania. cstefan58@yahoo.com

Oftalmologia (Bucharest, Romania : 1990)

|June 12, 2008

Summary

This summary is machine-generated.

Systane eye drops significantly reduced dry eye symptoms and improved ocular surface health after cataract surgery. Patients using Systane reported fewer discomforts and better tear film stability compared to those using purified water.

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Published on: July 7, 2023

Area of Science:

Ophthalmology
Ocular Surface Disease
Postoperative Care

Background:

Cataract surgery, particularly phacoemulsification, can impact tear film production and ocular surface health.
Postoperative inflammation and dryness are common complications following cataract surgery.

Purpose of the Study:

To evaluate the efficacy of Systane in managing subjective and objective signs of ocular discomfort post-cataract surgery.
To measure the effect of Systane on tear film stability and ocular surface healing.

Main Methods:

A 6-month, prospective, double-masked study involving two groups of patients post-cataract surgery.
Group A received Systane, while Group B received purified water, alongside standard postoperative treatment.
Ocular comfort questionnaires, Schirmer 1 test, tear break-up time (TBUT), and fluorescein staining were used for assessment.

Main Results:

Systane treatment led to a significant reduction in subjective dry eye symptoms compared to purified water (94.73% vs. 70.58% at 3 weeks).
Systane improved tear film stability (TBUT) and reduced epithelial defects, with only 5.26% of patients showing altered TBUT compared to 23.52% in the control group.
Schirmer 1 test results and fluorescein staining indicated better ocular surface health in the Systane group.

Conclusions:

Systane effectively prevents and treats tear film insufficiency symptoms and signs post-cataract surgery.
The use of Systane decreases postoperative complications and promotes epithelial repair, contributing to a healthier ocular surface.
Systane enhances patient satisfaction by maintaining a stable and healthy ocular surface after surgery.