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Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Ophthalmic Drug Delivery Systems

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Related Experiment Video

Updated: Jul 4, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

Phakic intraocular lenses.

Ladan Espandar1, Jay J Meyer, Majid Moshirfar

  • 1Department of Ophthalmology and Visual Sciences, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA.

Current Opinion in Ophthalmology
|June 12, 2008
PubMed
Summary

Phakic intraocular lenses offer predictable and safe vision correction for myopia. Advances in design and imaging enhance visual outcomes, though long-term risks require monitoring.

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Biomedical Engineering

Background:

  • Phakic intraocular lenses (PIOLs) are increasingly used in refractive surgery.
  • Recent advancements in PIOL design and materials have improved predictability, safety, and efficacy.

Purpose of the Study:

  • To review recent advancements in phakic intraocular lenses reported in 2007.
  • To update readers on the latest developments in PIOL technology and outcomes.

Main Methods:

  • Literature review of studies published in 2007 concerning PIOLs.
  • Analysis of visual outcomes, long-term complications, and imaging technologies related to PIOLs.

Main Results:

  • PIOLs demonstrate superior visual outcomes compared to other refractive surgeries for moderate to high myopia.

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Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
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Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

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Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

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  • Studies highlight long-term risks including endothelial cell loss, cataract formation, retinal detachment, and choroidal neovascularization.
  • Advanced imaging technologies (OCT, Scheimpflug) aid in custom PIOL design and accurate sizing.
  • Conclusions:

    • Long-term concerns regarding endothelial cell loss and cataract formation persist.
    • Proper PIOL sizing and positioning are crucial, facilitated by new imaging modalities.
    • Enhanced PIOL design, safety, predictability, and visual quality make them valuable for severe ametropia correction.