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Related Experiment Video

Updated: Jul 4, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Flow velocity estimation using joint Spectral and Time domain Optical Coherence Tomography.

Maciej Szkulmowski1, Anna Szkulmowska, Tomasz Bajraszewski

  • 1Institute of Physics, Nicolaus Copernicus University, ul. Grudziadzka 5, PL87-100 Torun, Poland.

Optics Express
|June 12, 2008
PubMed
Summary

We introduce joint Spectral and Time domain Optical Coherence Tomography (joint STdOCT), a novel method for measuring flow velocities. This technique offers more robust and sensitive blood flow measurements, especially in challenging imaging conditions.

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Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
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Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

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Last Updated: Jul 4, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

Area of Science:

  • Biomedical Optics
  • Medical Imaging Technology

Background:

  • Spectral Optical Coherence Tomography (SOCT) is a key imaging modality.
  • Accurate measurement of flow velocities is crucial for diagnosing various conditions.

Purpose of the Study:

  • To introduce and validate a modified SOCT method for enhanced flow velocity measurements.
  • To compare the performance of the new method against existing techniques.

Main Methods:

  • Developed joint Spectral and Time domain Optical Coherence Tomography (joint STdOCT).
  • Employed time-dependent spectral fringe acquisition and dual Fourier transformations (time and optical frequency domains).
  • Compared joint STdOCT with phase-resolved SOCT for flow velocity estimation.

Main Results:

  • Joint STdOCT provides more robust velocity estimations, particularly with low signal-to-noise ratio (SNR).
  • The method demonstrates superior sensitivity compared to phase-resolved SOCT.
  • Successfully applied to in vivo retinal blood circulation measurements.

Conclusions:

  • Joint STdOCT is a promising advancement for accurate and sensitive flow velocity quantification.
  • The method shows significant potential for in vivo biomedical imaging, including retinal diagnostics.
  • Applicability across different measurement modes (CCD exposure times) is demonstrated.