Related Experiment Video
Updated: Jul 4, 2026

Automated Microbial Cultivation and Adaptive Evolution using Microbial Microdroplet Culture System (MMC)
Published on: February 18, 2022
Development of a direct digital-controlled fermentor using a microminicomputer hierarchical system
M J Rolf1, P J Hennigan, R D Mohler
1School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907.
A new computerized fermentation system offers flexibility and versatility for research. Its direct digital control and microcomputer configuration ensure accurate data acquisition and precise fermentation control.
Area of Science:
- Biotechnology and biochemical engineering
- Automation and control systems
Background:
- Traditional fermentation systems often lack flexibility and advanced control capabilities.
- Research environments require adaptable and precise tools for microbial cultivation.
Purpose of the Study:
- To design and construct a versatile computerized fermentation system for research applications.
- To implement direct digital control for enhanced operational precision.
Main Methods:
- Development of a hierarchical control structure using a microminicomputer.
- Integration of direct digital control for all low-level and high-level control loops.
- Simplification of hardware and software interfaces through microcomputer utilization.
Main Results:
- The system provides accurate data acquisition capabilities.
- Excellent control over fermentation parameters is achieved.
- High flexibility in managing fermentation operations is demonstrated.
Conclusions:
- The developed computerized fermentation system meets the goals of flexibility and versatility.
- It offers a robust platform for advanced research in fermentation technology.
- The system enhances the efficiency and reliability of fermentation processes.
More Related Videos
12:04Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation
Published on: December 6, 2013
11:13Design and Implementation of an Automated Illuminating, Culturing, and Sampling System for Microbial Optogenetic Applications
Published on: February 19, 2017
Related Concept Videos
Bioreactor Controls-I
Scale-Up Processes
Bioreactor Controls-II
Microbial Fermentation
Bioreactor Controls-III
Bioreactor Design and Operational System