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Updated: Sep 20, 2026

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
Published on: June 7, 2018
[Computer analysis of the dynamics of two tumor foci with respect to circulating immune cells]
Abstract:
A mathematical model of the bilocal immunogenic tumors was analysed by a computer. An increase of the intensity or/and growth of asymmetry in cytotoxic cells migration between two tumor centres could lead to bifurcations in the system. This approach allows interpretation of a number of paradoxes in the interrelations between the original tumor and metastases.
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