[Ca+-dependent efflux of K+ from erythrocytes, induced by an oxidative process]

Effects of inhibitors of energetic processes, antioxidants and SH-reagents on Ca(2+)-dependent K+ efflux from human red blood cells induced by oxidizing agents, electron donor system ascorbate + phenazine methosulphate (PMS) and Na periodate were investigated. We concluded that different regulatory mechanisms of K+ efflux from cells existed. In contract to periodate effect, Ca(2+)-dependent K+ channel activated by ascorbate + PMS is functionally connected with the membrane redox components.