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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
Cancer Vaccines01:30

Cancer Vaccines

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Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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Bacterial Signaling

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

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Breast implants as a preventive factor.

N Vincent1, L Barletta, M Laguens

  • 1International Society of Aesthetic Plastic Surgery, Hanover, NH 03755, USA. vincent@elsitio.net

Aesthetic Plastic Surgery
|June 14, 2008
PubMed
Summary
This summary is machine-generated.

Silicone breast implants are not carcinogenic. In rats, implants caused localized skin temperature changes (dysthermia) and neutralized hormonal effects, while non-implanted glands showed alterations.

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Oncology

Background:

  • Previous large-scale evaluations confirmed silicone breast implants are non-carcinogenic.
  • This established safety allowed for further investigation into implant-related physiological effects.
  • Research is needed to understand the localized biological responses to silicone implants.

Purpose of the Study:

  • To investigate the physiological effects of silicone breast implants in a rat model.
  • To assess localized temperature changes and hormonal interactions associated with implants.
  • To compare the biological responses of implanted versus non-implanted mammary glands.

Main Methods:

  • Temperature measurements using a high-precision monitor in 100 silicone-implanted rats.
  • Grouping of rats based on hormone levels to compare implanted and non-implanted mammary glands.
  • Analysis and comparison of temperature data and glandular morphology.

Main Results:

  • Localized dysthermia (abnormal temperature) was detected in the skin overlying the silicone implants.
  • Silicone implants demonstrated a neutralizing effect on hormonal activity at high hormone levels.
  • Non-implanted mammary glands exhibited significant glandular alterations, including anisocytosis and anisokoryosis.

Conclusions:

  • Silicone breast implants do not pose a carcinogenic risk.
  • Implants induce localized thermal changes and can modulate hormonal responses.
  • Mammary glands without implants showed more pronounced pathological alterations under similar hormonal conditions.