Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Liver diseases in the elderly.

J R Levinson1, S C Gordon

  • 1Gastroenterology Training Program, Sinai Hospital, Detroit, Michigan.

Clinics in Geriatric Medicine
|May 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trends in Scope of Practice for Oral Health Care: Future Transformative Effects.

JDR clinical and translational research·2022
Same author

Hepatocellular Carcinoma Surveillance in a Cohort of Chronic Hepatitis C Virus-Infected Patients with Cirrhosis.

Journal of gastrointestinal cancer·2019
Same author

Rebound effect associated with JAK inhibitor use in the treatment of alopecia areata.

Journal of the European Academy of Dermatology and Venereology : JEADV·2018
Same author

Impact of sustained virologic response on risk of type 2 diabetes among hepatitis C patients in the United States.

Journal of viral hepatitis·2018
Same author

Hepatitis C virus re-treatment in the era of direct-acting antivirals: projections in the USA.

Alimentary pharmacology & therapeutics·2018
Same author

HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry.

HLA·2017
Same journal

Cardiovascular Prevention in Older Adults: From Estimation to Treatment.

Clinics in geriatric medicine·2026
Same journal

Preventive Cardiology for the Clinically Complex Older Adult.

Clinics in geriatric medicine·2026
Same journal

A Preventive Neurology Perspective on Promoting Brain Health and Preventing Cardiovascular Disease.

Clinics in geriatric medicine·2026
Same journal

Secondary Prevention in Older Adults: Putting It All Together.

Clinics in geriatric medicine·2026
Same journal

Primary Prevention in Older Adults: Putting It All Together.

Clinics in geriatric medicine·2026
Same journal

Managing Bleeding Risk in Older Adults: Antithrombotics and Anticoagulants.

Clinics in geriatric medicine·2026
See all related articles

Cirrhosis evaluation in the elderly requires careful investigation beyond presumed alcoholic liver disease. Early diagnosis and appropriate treatment of various liver conditions in older adults are crucial for better outcomes.

Area of Science:

  • Hepatology
  • Geriatric Medicine
  • Internal Medicine

Background:

  • Cirrhosis is prevalent in the elderly, but its causes are often misattributed, particularly to alcohol.
  • Older patients may be incorrectly diagnosed with alcoholic liver disease, necessitating a broader differential diagnosis.

Purpose of the Study:

  • To outline the diverse etiologies of cirrhosis in the elderly population.
  • To emphasize the importance of thorough investigation and appropriate diagnostic workup for liver disease in older adults.
  • To discuss current and emerging therapeutic strategies for various liver conditions in the geriatric population.

Main Methods:

  • Review of existing literature and clinical experience regarding cirrhosis in the elderly.
  • Diagnostic workup including serological tests for hepatitis B and C, antimitochondrial antibodies, and alpha 1-antitrypsin levels.

Related Experiment Videos

  • Consideration of hepatotoxic drug exposure and cardiac cirrhosis.
  • Evaluation of liver biopsy risks and benefits in elderly patients.
  • Assessment of treatment options for specific liver diseases and complications.

    • Main Results:

    • Alcohol is often overestimated as the cause of cirrhosis in the elderly; nonalcoholic causes are frequently identified.
    • Hepatotoxic drugs, viral hepatitis (B and C), primary biliary cirrhosis, cardiac cirrhosis, alpha 1-antitrypsin deficiency, and autoimmune hepatitis are important considerations.
    • Advanced age is not a contraindication for many treatments, including variceal sclerotherapy, paracentesis, and liver transplantation.
    • Specific treatments like colchicine, methotrexate, ursodeoxycholic acid, corticosteroids, phlebotomy, and interferons show promise.

    Conclusions:

    • Comprehensive evaluation is essential to accurately diagnose cirrhosis in the elderly, moving beyond assumptions of alcoholic etiology.
    • Modern treatments and interventions for liver disease and its complications are safe and effective in geriatric patients.
    • Liver disease management in the elderly presents diagnostic challenges but offers rewarding therapeutic opportunities.