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Published on: September 22, 2023
[Asthma and rhinitis in childhood]
1Medizinische Universitäts-Kinderklinik, Kinderspital Zürich. felix.sennhauser@kispi.uzh.ch
Insights
Childhood asthma and rhinitis share underlying inflammation, impacting the upper and lower airways. Early diagnosis and treatment of allergic rhinitis are crucial for managing the rhinobronchial syndrome in children.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
- Pediatric Otolaryngology
Context:
- Bronchial asthma is a prevalent chronic childhood illness (7-15% in Switzerland), often diagnosed clinically due to lack of objective criteria in infants.
- Allergic mechanisms contribute to up to 80% of asthma cases in school-aged children.
- Upper and lower airways are functionally interconnected (united airways), meaning nasal conditions can affect respiratory health.
Purpose:
- To highlight the common inflammatory basis of bronchial asthma and rhinitis in children.
- To emphasize the diagnostic challenges in early childhood asthma.
- To underscore the significance of the rhinobronchial syndrome.
Summary:
- Asthma involves intrathoracic respiratory mucosa inflammation; allergic triggers are common in older children.
- Rhinitis etiology shifts from viral in infants to allergic in school-aged children, often leading to rhinosinusitis.
- Therapy includes bronchodilators and topical steroids for asthma, and topical steroids for allergic rhinitis, with antibiotics rarely needed.
Impact:
- Recognizing the united airways concept is vital for understanding and managing pediatric respiratory conditions.
- Effective management of allergic rhinitis with topical steroids may prevent complications like bronchial obstruction.
- This understanding supports integrated treatment approaches for the rhinobronchial syndrome.
Abstract:
Bronchial asthma is the most common chronic disease in childhood with a cumulative prevalence of 7-15% in Switzerland. The diagnosis is based on clinical findings due to a lack of objective criteria especially in infants and toddlers. The common base of all asthmatics is an inflammation of the intrathoracic respiratory mucosa. In school-age children allergic mechanisms are documented in up to 80%. Asthma therapy consists of symptom relief by bronchodilators and of antiinflammatory topical steroids. Rhinitis in early childhood is mainly caused by viral infections whereas in school-age children allergic inflammation becomes the main cause. During inflammatory processes of the nose the mucosa of the sinus is affected too causing rhinosinusitis. In infants therapy is normally restricted to symptom relief. The treatment of choice in allergic rhinitis are topical steroids. Antibiotics are rarely indicated. Infants with obstructed nose are prone to severe complications because of exclusive nasal breathing in this age period. The upper and lower airways are functionally linked by different mechanisms (united air ways). Patients with rhinitis often suffer from variable bronchial airflow obstruction and (sub)clinical asthma causing the so-called rhinobronchial syndrome.
Related Concept Videos
Asthma I: Introduction
Asthma-I: Introduction
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma III: Clinical Manifestations
Asthma-III: Symptoms and Complications
Classification of Asthma

