Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Legionella infection.

M L Nguyen1, V L Yu

  • 1Department of Medicine, Montefiore University Hospital, Pittsburgh, Pennsylvania.

Clinics in Chest Medicine
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Legionella bacteria commonly cause hospital and community pneumonia, especially in at-risk patients. Prompt identification and disinfection of water systems are key to controlling Legionella outbreaks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of bud and anther morphology with developmental stages of the male gametophyte of melon (Cucumis melo L.).

Vavilovskii zhurnal genetiki i selektsii·2022
Same author

Discovery and hit-to-lead evaluation of piperazine amides as selective, state-dependent Na<sub>V</sub>1.7 inhibitors.

MedChemComm·2018
Same author

Indications and pregnancy outcomes when multidisciplinary centers for prenatal diagnosis refuse request for termination of pregnancy: a retrospective French study.

Prenatal diagnosis·2013
Same author

Pancreatic inflammation and increased islet macrophages in insulin-resistant juvenile primates.

The Journal of endocrinology·2013
Same author

The effect of urease and nitrification inhibitors on ammonia and nitrous oxide emissions from simulated urine patches in pastoral system: a two-year study.

The Science of the total environment·2013
Same author

Outcomes and follow-up of patients treated for multidrug-resistant tuberculosis in Orel, Russia, 2002-2005.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2012
Same journal

Pneumonia Reimagined: Host, Microbe, and the Shifting Landscape of Disease.

Clinics in chest medicine·2026
Same journal

Advocacy in Pneumonia.

Clinics in chest medicine·2026
Same journal

Vaccines Against Pneumonia: Current Updates.

Clinics in chest medicine·2026
Same journal

Non-antibiotic Treatments for Pneumonia: Host-Directed Therapies, Next-Steps and Future Directions.

Clinics in chest medicine·2026
Same journal

Customizing Antibiotic Treatment for Pneumonia: Can We Have a Single Unified Algorithm for All Types of Pneumonia?

Clinics in chest medicine·2026
Same journal

The Role of Complex Digital Interventions to Improve Pneumonia Care.

Clinics in chest medicine·2026
See all related articles

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Legionella species are increasingly recognized as significant causes of both hospital-acquired (nosocomial) and community-acquired pneumonia.
  • Certain patient populations, including those with chronic lung disease and organ transplant recipients, face a heightened risk of severe Legionella infection.
  • The clinical presentation of Legionella pneumonia is often non-specific, complicating early diagnosis.

Purpose of the Study:

  • To review the epidemiology, clinical features, and management of Legionella pneumonia.
  • To highlight the importance of environmental surveillance for Legionella in healthcare settings.
  • To discuss effective disinfection strategies for water systems to prevent Legionella transmission.

Main Methods:

Related Experiment Videos

  • Literature review of studies on Legionella species and associated pneumonia.
  • Analysis of clinical manifestations and risk factors for Legionella infection.
  • Evaluation of diagnostic approaches and treatment options, including antibiotic choices.
  • Assessment of environmental control measures for Legionella in water systems.

Main Results:

  • Legionella is a frequent cause of pneumonia, particularly in immunocompromised individuals and those with underlying respiratory conditions.
  • Key clinical indicators include high fever (often >39°C) and diarrhea, though symptoms can be variable.
  • Erythromycin is the primary antibiotic, with alternative effective agents available.
  • Environmental sampling of water systems and respiratory equipment can confirm sources of infection.
  • Effective disinfection methods like superheating/flushing and hyperchlorination are feasible for water systems.

Conclusions:

  • Legionella pneumonia requires prompt recognition and appropriate antibiotic therapy.
  • Environmental control and disinfection of water systems are crucial for preventing and managing Legionella outbreaks in healthcare facilities.
  • Early detection and source identification are vital for patient outcomes and public health protection.