[Etiologic identification of chronic cough by bronchofibroscopy in children]

Yi Yu1, Ying-Shuo Wang, Zhi-Min Chen

  • 1Department of Respiratory Medicine, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. yuyi413@126.com

Insights

Bronchofibroscopy effectively identifies causes of chronic cough in children. This procedure is valuable for diagnosing conditions like respiratory infections and foreign bodies, aiding in timely treatment.

Area of Science:

  • Pediatric Pulmonology
  • Diagnostic Bronchoscopy
  • Respiratory Medicine

Context:

  • Chronic cough in children often presents diagnostic challenges.
  • Etiologic identification is crucial for effective management.
  • Bronchofibroscopy offers a direct visualization method.

Purpose:

  • To evaluate the diagnostic utility of bronchofibroscopy for chronic cough in pediatric patients.
  • To determine the range of etiologies identified by bronchofibroscopy.

Summary:

  • Bronchofibroscopy was performed on 118 children (3 months–13 years) with unexplained chronic cough.
  • The procedure successfully identified the cause in 115 cases.
  • Common causes included respiratory infections (39), foreign bodies (19), and asthma (17).

Impact:

  • Bronchofibroscopy is a valuable tool for diagnosing the causes of chronic cough in children.
  • It facilitates targeted therapeutic interventions.
  • This supports improved patient outcomes in pediatric respiratory care.
Abstract

Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations01:19

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...