Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Long-term oncological outcomes and morbidity and mortality associated with radical hysterectomy by laparoscopy versus laparotomy for early-stage cervical cancer].

Gynecologie, obstetrique, fertilite & senologie·2026
Same author

Efficacy of drug regimens containing omadacycline in a murine model of <i>Mycobacterium avium</i> chronic lung infection.

Frontiers in microbiology·2026
Same author

Longitudinal orientation of temporal artery biopsy for the diagnosis of giant cell arteritis: A cross-sectional study.

Seminars in arthritis and rheumatism·2026
Same author

Chronic cadmium exposure promotes TRPM7-dependent acquisition of a myofibroblast-like phenotype in pancreatic stellate cells.

Cell biology and toxicology·2026
Same author

A Recurrent Blood Culture-Negative Endocarditis Revealing Whipple's Disease.

JACC. Case reports·2026
Same author

Impact of histological healing on ulcerative colitis disease course among patients with endoscopic healing: results of a prospective study.

Clinics and research in hepatology and gastroenterology·2025

Related Experiment Video

Updated: Jul 4, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

[Anal and anal margin tumors].

Denis Chatelain1, Nassima Mokrani, Jean-François Fléjou

  • 1Service d'anatomie pathologique, CHU Amiens, Place Victor-Pauchet, 80054 Amiens cedex 01. Chatelain.denis@chu-amiens.fr

Annales De Pathologie
|June 17, 2008
PubMed
Summary

This study examines rare anal canal and anal margin tumors, detailing their pathological challenges. It covers common benign growths like condylomas and rare cancers such as squamous cell carcinoma.

Area of Science:

  • Pathology
  • Oncology

Context:

  • Tumors of the anal canal and anal margin are uncommon, presenting unique diagnostic challenges for pathologists.
  • Understanding the spectrum of anal neoplasms is crucial for accurate diagnosis and patient management.

Purpose:

  • To provide a comprehensive overview of the pathological features of benign and malignant tumors affecting the anal canal and anal margin.
  • To highlight the diagnostic difficulties associated with these rare neoplasms.

Summary:

  • Benign anal tumors primarily include condylomas, cloacogenic polyps, and fibro-epithelial polyps.
  • Malignant anal tumors are infrequent, predominantly well-differentiated or poorly differentiated basaloid squamous cell carcinoma, with other malignant types being exceedingly rare.
  • Pathological examination is key to differentiating benign from malignant anal lesions.

More Related Videos

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
04:45

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
10:38

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens

Published on: February 1, 2020

Related Experiment Videos

Last Updated: Jul 4, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
04:45

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
10:38

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens

Published on: February 1, 2020

Impact:

  • This review aids pathologists in the accurate identification and classification of anal canal and anal margin tumors.
  • Improved understanding of these rare tumors can lead to more precise diagnostic strategies and potentially influence treatment planning.