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Pediatric renal transplantation: a single-center experience

A Vasudevan1, A Iyengar, B Jose

  • 1Children's Kidney Care Centre, St. John's Medical College Hospital, Bangalore, India.

Transplantation Proceedings
|June 17, 2008
PubMed

Insights

Pediatric renal transplants show promising outcomes, with high graft survival rates at 5 years. Urinary tract infections were the most common complication following these kidney transplant procedures.

Area of Science:

  • Pediatric Nephrology
  • Transplant Surgery
  • Immunology

Background:

  • Renal transplantation is a critical treatment for pediatric end-stage renal disease.
  • Understanding outcomes and complications in pediatric kidney transplant recipients is essential for improving patient care.

Purpose of the Study:

  • To analyze the outcomes of pediatric renal transplants over an 8-year period.
  • To identify common complications and survival rates in this patient population.

Main Methods:

  • Retrospective analysis of 33 pediatric renal transplants.
  • Data collected included patient demographics, underlying renal disease, dialysis duration, donor type, post-transplant complications, immunosuppression protocols, and graft survival rates.

Main Results:

  • The mean age was 12.5 years, with 26 boys and 7 girls. Glomerular and tubulointerstitial diseases were the primary indications.
  • Living related donors were most common. Urinary tract infection was the most frequent post-transplant complication.
  • Actuarial graft survival rates were 94% at 1 year, 90% at 3 years, and 82% at 5 years.

Conclusions:

  • Pediatric renal transplantation demonstrates favorable long-term graft survival.
  • Effective management of complications like urinary tract infections is crucial for successful transplant outcomes in children.

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