Related Experiment Video
Updated: Jul 4, 2026
18:50
Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Inflow into saccular cerebral aneurysms at arterial bends
Yohsuke Imai1, Kodai Sato, Takuji Ishikawa
1Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 6-6-01 Aramaki Aza Aoba, Aoba-ku, Sendai-shi, Miyagi, 980-8579, Japan. yimai@pfsl.mech.tohoku.ac.jp
Annals of Biomedical Engineering
|June 20, 2008
Summary
Investigating aneurysm inflow at arterial bends revealed that artery shape and aneurysm angle significantly impact flow patterns. Secondary flow in the parent artery is the primary driver, crucial for designing better endovascular devices.
Area of Science:
- Biomedical Engineering
- Cardiovascular Research
- Fluid Dynamics
Background:
- Conventional endovascular devices face design challenges.
- Aneurysm inflow dynamics are complex and influenced by vascular geometry.
Purpose of the Study:
- To identify shortcomings in current endovascular device designs.
- To investigate aneurysm inflow characteristics at various arterial bends.
Main Methods:
- Computational fluid dynamics (CFD) simulations were employed.
- Steady-state inflow was analyzed for aneurysms in U-shaped, twisted, and S-shaped arteries.
Main Results:
- Arterial geometry and aneurysm configuration angle significantly influenced inflow patterns and flux.
- Secondary flow within the parent artery was identified as the dominant factor affecting inflow.
Conclusions:
- Arterial geometry and secondary flow are critical considerations for endovascular device design.
- Improved device designs should account for complex hemodynamic factors in aneurysms.
Related Concept Videos
01:30Aneurysm I: Introduction
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
01:10The Arch of Aorta
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Encircling the heart, the coronary arteries form a ring-like structure before...
01:26Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
01:19Anastomoses
In human anatomy, anastomosis refers to a connection or opening between two things, particularly between blood vessels or other tubular structures. The term is derived from the Greek term 'anastomosis,' which means 'outlet' or 'opening.' This natural network of connections plays a critical role in the survival and functionality of the human body.
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
Arterial Anastomosis: These occur between arteries. They are most common in...
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
Arterial Anastomosis: These occur between arteries. They are most common in...
01:26Arteries of the Head and Neck
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...