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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Long-pulsed dye laser versus intense pulsed light for photodamaged skin: a randomized split-face trial with blinded
Gitte F Jørgensen1, Lene Hedelund, Merete Haedersdal
1Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Objective:
In a randomized controlled split-face trial to evaluate efficacy and adverse effects from rejuvenation with long-pulsed dye laser (LPDL) versus intense pulsed light (IPL).
Materials And Methods:
Twenty female volunteers with Fitzpatrick skin types I-III, classes I-II rhytids, and symmetrical split-face photodamage were included in the study. Subjects received a series of three treatments at 3-week intervals with half-face LPDL (V-beam Perfecta, 595 nm, Candela Laser Corporation) and half-face IPL (Ellipse Flex, Danish Dermatologic Development); the interventions being randomly assigned to left and right sides. Primary end-points were telangiectasias, irregular pigmentation and preferred treatment. Secondary end-points were skin texture, rhytids, pain, and adverse effects. Efficacy was evaluated by patient self-assessments and by blinded clinical on-site and photographic evaluations at 1, 3, and 6 months postoperatively. Adverse effects were evaluated by blinded clinical on-site evaluations.
Results:
Telangiectasia improved from LPDL and IPL treatments with superior vessel clearance from LPDL treatments (postoperative side-to-side evaluations, patient self-assessments, P
Conclusion:
This study was based on two specific laser and IPL equipments, which found LPDL rejuvenation advantageous to IPL rejuvenation due to superior vessel clearance and less pain.
