Low frequency of renal artery disease in young ischemic stroke patients

Tai-Cheng Wu1, Tsong-Hai Lee

  • 1Stroke Section, Department of Neurology, Chang Gung Memorial Hospital, LinKou Medical Center and College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Insights

Renal artery disease is uncommon in young ischemic stroke patients and not linked to typical risk factors. However, it is associated with intracranial carotid and coronary artery disease.

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Vascular Surgery

Background:

  • Renal artery disease (RAD) in young ischemic stroke patients remains understudied.
  • Associated risk factors and vascular comorbidities of RAD in this demographic are not well understood.

Purpose of the Study:

  • To investigate the frequency of renal artery disease in patients with ischemic stroke under 50 years old.
  • To identify associated vascular risk factors and comorbidities in young ischemic stroke patients with renal artery disease.

Main Methods:

  • Retrospective review of 152 ischemic stroke patients aged 50 or younger.
  • Inclusion of 30 older ischemic stroke patients as controls.
  • Performance of cerebral angiography and abdominal aortography to assess renal, cerebral, and coronary artery stenosis.

Main Results:

  • Renal artery disease was found in 4.6% of younger patients, with 1.3% having significant stenosis.
  • No significant association was observed between renal artery disease and traditional vascular risk factors (p > 0.05).
  • A higher frequency of renal artery disease was noted in patients with intracranial carotid and coronary artery disease (p < 0.05).

Conclusions:

  • The prevalence of renal artery disease is low among younger ischemic stroke patients.
  • Intracranial carotid artery disease and coronary artery disease are associated with renal artery disease in this population.
Abstract

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