Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

<i>Chrysanthemum coronarium</i> suppresses ferroptosis-driven vascular hyperplasia following carotid artery ligation in mice.

Food science and biotechnology·2026

Same author

Computational carrier dynamics across heterojunction interface between hole injection and transport layers in quantum-dot light-emitting diodes.

Scientific reports·2026

Same author

Long-term effects of preterm birth on cortical folding trajectories in early childhood.

Brain communications·2026

Same author

A comparative analysis of pig-to-rhesus corneal xenotransplantation with various immunosuppressive regimens.

Korean journal of ophthalmology : KJO·2026

Same author

Effect of water activity and light exposure on the stability of bioactive compounds in matcha (Camellia sinensis) powder during storage periods.

Food chemistry·2026

Same author

Ligand-Driven Tuning of Adsorption Energy in Nanocrystals for High-Performance H<sub>2</sub>O<sub>2</sub> Electrosynthesis.

Journal of the American Chemical Society·2026

Same journal

Unsupervised deep image prior for sparse-view and limited-angle electron tomography.

Ultramicroscopy·2026

Same journal

Determination of the structure of the tertiary phase in the alloy Al<sub>10</sub>Mo<sub>10</sub>Nb<sub>10</sub>Ta<sub>10</sub>Ti<sub>30</sub>Zr<sub>30</sub> using convergent beam electron diffraction.

Ultramicroscopy·2026

Same journal

Predictive drift compensation of multi-frame STEM via live scan modification.

Ultramicroscopy·2026

Same journal

Deep PACBED: Multitask analysis of PACBED images using deep neural networks.

Ultramicroscopy·2026

Same journal

Guided progressive reconstructive imaging: A new quantization-based framework for low-dose, high-throughput and real-time analytical ptychography.

Ultramicroscopy·2026

Same journal

Brightness optimization in a 200 keV DTEM source by geometry-driven aberration suppression.

Ultramicroscopy·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 4, 2026

Formation of Biomembrane Microarrays with a Squeegee-based Assembly Method

Formation of Biomembrane Microarrays with a Squeegee-based Assembly Method

Published on: May 8, 2014

Self-organized functional lipid vesicle array for sensitive immunoassay chip.

Hea Yeon Lee¹, Bong Kuk Lee, Jong Wan Park

¹The Institute of Scientific and Industrial Research, Osaka University, Osaka 567-0047, Japan. hylee@sanken.osaka-u.ac.jp

Ultramicroscopy

|June 21, 2008

Summary

This summary is machine-generated.

Functional lipid vesicles (FLVs) were immobilized onto nanosized geometrics using electrostatic interactions. This method enables the development of novel nanobiosensors and drug delivery systems.

More Related Videos

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

Published on: March 17, 2023

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

Published on: July 27, 2017

Related Experiment Videos

Last Updated: Jul 4, 2026

Formation of Biomembrane Microarrays with a Squeegee-based Assembly Method

Formation of Biomembrane Microarrays with a Squeegee-based Assembly Method

Published on: May 8, 2014

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

Published on: March 17, 2023

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

Published on: July 27, 2017

Area of Science:

Biomaterials Science
Nanotechnology
Electrochemistry

Background:

Lipid vesicles are crucial for biological functions and drug delivery.
Controlling vesicle arrangement is key for advanced applications.
Existing immobilization techniques face challenges in maintaining vesicle integrity and function.

Purpose of the Study:

To develop a method for self-assembly immobilization of functional lipid vesicles (FLVs).
To investigate the electrostatic interactions for vesicle arrangement on nanosized geometrics.
To evaluate the electrochemical properties and sensing capabilities of immobilized FLVs.

Main Methods:

Utilized electrostatic interactions for self-assembly of FLVs onto N-inscription-nanosized geometrics.
Employed Atomic Force Microscopy (AFM) to characterize the three-dimensional structures of immobilized liposomes.
Performed electrochemical measurements to assess redox activity and antigen-binding events.

Main Results:

Achieved well-organized, individual arraying of FLVs on nanosized surfaces.
Demonstrated clear redox activity of the immobilized FLVs.
Observed a significant current decrease upon binding of capture antibodies to human serum albumin (HSA) antigen, indicating successful biosensing.

Conclusions:

The electrostatic self-assembly method effectively immobilizes functional lipid vesicles.
Immobilized FLVs exhibit promising electrochemical sensing capabilities for applications like nanobiosensors.
This technique holds potential for drug delivery systems and nano-scale membrane studies.