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Related Concept Videos

Phylogenetic Trees03:21

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.The length of the branches can depict time or the relative amount of change among organisms. For instance, the branch length might indicate the number of amino acid changes in the sequence that underlies the...
Phylogenetic Trees03:21

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.The length of the branches can depict time or the relative amount of change among organisms. For instance, the branch length might indicate the number of amino acid changes in the sequence that underlies the...
Survival Tree01:19

Survival Tree

Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
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Microbial Phylogeny01:28

Microbial Phylogeny

Understanding the evolutionary relationships among microorganisms is fundamental to microbial ecology and taxonomy. Phylogenetic trees are essential tools for inferring these relationships, relying primarily on comparative analyses of molecular sequences such as DNA, RNA, or proteins. In microbial studies, these trees typically depict the evolutionary paths of diverse bacterial and archaeal species by mapping genetic differences accumulated over time.Phylogenetic trees are composed of tips,...
Phylogeny01:23

Phylogeny

Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire...
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

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A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

Inferring trees.

Simon Whelan1

  • 1Faculty of Life Sciences, University of Manchester, Manchester, UK.

Methods in Molecular Biology (Clifton, N.J.)
|June 21, 2008
PubMed
Summary
This summary is machine-generated.

This study introduces molecular phylogenetics and phylogenetic tree estimation. It details inferential methods, algorithms, and practical guidelines for analyzing evolutionary relationships between biological sequences.

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Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
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Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

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Last Updated: Jul 4, 2026

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Area of Science:

  • Evolutionary biology
  • Bioinformatics
  • Computational biology

Background:

  • Molecular phylogenetics analyzes the evolution of biological sequences and their historical relationships.
  • Phylogenetic trees are crucial for visualizing these evolutionary connections.

Purpose of the Study:

  • To provide an introduction to evolutionary trees and inferential methodologies.
  • To discuss assumptions, algorithms, and practical aspects of phylogenetic tree estimation.
  • To compare Bayesian and maximum likelihood approaches in phylogenetics.

Main Methods:

  • Review of commonly used inferential methodologies in molecular phylogenetics.
  • Detailed discussion of algorithms for phylogenetic tree estimation.
  • Exploration of assumptions and their impact on phylogenetic analysis.

Main Results:

  • Understanding of how sequence evolution informs historical relationships.
  • Insight into various algorithms for constructing phylogenetic trees.
  • Awareness of the influence of assumptions on phylogenetic inference.

Conclusions:

  • Effective phylogenetic tree estimation requires careful consideration of methods and assumptions.
  • Combining software packages can enhance inference accuracy.
  • Bayesian and maximum likelihood methods offer distinct advantages in phylogenetic analysis.