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Reliability of different image analysis methods for scanning laser Doppler flowmetry
Andreas J Kreis1, Thanh Nguyen, Sophie Rogers
1Centre for Eye Research Australia, University of Melbourne, Australia.
Purpose:
To assess reliability and reproducibility of different analysis methods for retinal capillary flow, volume, and velocity from scanning laser Doppler flowmetry (SLDF) topography.
Material And Methods:
SLDF topography analysis using the default retinal flowmeter (HRF) were compared to that using automatic full-field perfusion image analyzer (AFFPIA) and quantified as intraclass correlation coefficients (ICC).
Results:
The AFFPIA full-field method had the highest reliability, with ICC 0.99 for capillary flow. The reproducibility using the AFFPIA full-field method was high ICC 0.74 for capillary flow.
Conclusions:
The AFFPIA full-field method is highly reliable and superior to the default HRF software.
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