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An Efficient and Rapid HPLC-QQQ-MS Method for the Quantitation of Tropane Alkaloids in Medicinal Plants
Published on: June 12, 2026
Secondary metabolites from Tectona philippinensis
Consolacion Y Ragasa1, Maria Claribel Lapina, Jadz Jevz Lee
1Chemistry Department, De La Salle University, 1004 Manila. ragasac@dlsu.edu.ph
Abstract:
The air-dried leaves of Tectona philippinensis, an endemic and endangered Philippine medicinal plant, afforded 5-hydroxy-3,7,4'-trimethoxyflavone (1), 5,4'-dihydroxy-3,7-dimethoxyflavone (2), squalene (3), a mixture of lupeol (4a) and beta-amyrin (4b), chlorophyllide a (5), and hydrocarbons. Antimicrobial tests on 1 and 2 indicated low antifungal activity against the fungi, Candida albicans and Trichophyton mentagrophytes. Compound 1 was also found to have low antibacterial activity against Escherichia coli and Pseudomonas aeruginosa.
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