Related Experiment Videos
Pseudomonas scleritis resistant to fourth-generation fluoroquinolones in a patient without prior trauma or surgery
Jay J Meyer1, Ladan Espandar, Douglas P Marx
1University of Utah, Ophthalmology, John Moran Eye Center, Salt Lake City, Utah, USA.
Purpose:
To describe a case of necrotizing scleritis due to Pseudomonas aeruginosa resistant to fourth-generation fluoroquinolones.
Methods:
Case report. A 50-year-old woman with no history of trauma or surgery presented with pain and redness of the left eye.
Results:
The patient did not respond to empiric treatment and developed scleral edema with a nummular area of avascular sclera nasally. Histopathologic examination revealed necrotizing scleritis and cultures grew P. aeruginosa resistant to fourth-generation fluoroquinolones.
Conclusions:
A high index of suspicion for an infectious etiology must be maintained in cases not responding to conventional noninfectious scleritis therapy and in cases with unusual presentations. Resistance to commonly used empiric antibiotics may further complicate the diagnosis and management of infectious scleritis.
Related Concept Videos
Inhibitors of Bacterial DNA Synthesis
Acute Pyelonephritis II: Diagnostic Studies and Management
Mechanism of Antibiotic Resistance in MRSA
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care