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Related Concept Videos

Radical Oxidation of Allylic and Benzylic Alcohols01:21

Radical Oxidation of Allylic and Benzylic Alcohols

Activated manganese(IV) oxide can selectively oxidize allylic and benzylic alcohols via a radical intermediate mechanism. Primary allylic alcohols are oxidized to aldehydes, while secondary allylic alcohols yield ketones. The redox reaction of potassium permanganate with an Mn(II) salt such as manganese sulfate (under either alkaline or acidic conditions), followed by thorough drying, yields the oxidizing agent: activated MnO2. While MnO2 is insoluble in the solvents used for the reaction, the...
Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate02:21

Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate

Alkenes can be dihydroxylated using potassium permanganate. The method encompasses the reaction of an alkene with a cold, dilute solution of potassium permanganate under basic conditions to form a cis-diol along with a brown precipitate of manganese dioxide.
Oxidation of Alcohols02:37

Oxidation of Alcohols

In this lesson, the oxidation of alcohols is discussed in depth. The various reagents used for oxidation of primary and secondary alcohols are detailed, and their mechanism of action is provided.
The process of oxidation in a chemical reaction is observed in any of the three forms:
Electron Transport Chain: Complex III and IV01:43

Electron Transport Chain: Complex III and IV

During the electron transport chain, electrons from NADH and FADH2 are first transferred to complexes I and II, respectively. These two complexes then transfer the electrons to ubiquinol, which carries them further to complex III. Complex III passes the electrons across the intermembrane space to Cyt c, which carries them further to complex IV. Complex IV donates electrons to oxygen and reduces it to water. As electrons pass through complexes I, III, and IV, the energy released aids the pumping...
Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids02:04

Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

Diols are compounds with two hydroxyl groups. In addition to syn dihydroxylation, diols can also be synthesized through the process of anti dihydroxylation. The process involves treating an alkene with a peroxycarboxylic acid to form an epoxide. Epoxides are highly strained three-membered rings with oxygen and two carbons occupying the corners of an equilateral triangle. This step is followed by ring-opening of the epoxide in the presence of an aqueous acid to give a trans diol.
Radical Autoxidation01:20

Radical Autoxidation

The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...

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Unexpected dispersion-stabilized tris(terphenylthiolate) complexes, Ln(SAr <sup><i>i</i>Pr6</sup>)<sub>3</sub>, arising from two-electron reduction by Ln(SAr <sup><i>i</i>Pr6</sup>)<sub>2</sub> [Ar <sup><i>i</i>Pr6</sup> = C<sub>6</sub>H<sub>3</sub>-2,6-(C<sub>6</sub>H<sub>2</sub>-2,6,4- <sup><i>i</i></sup> Pr<sub>3</sub>)<sub>2</sub>].

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Updated: Jul 4, 2026

Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts
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Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts

Published on: August 7, 2018

A monomeric Mn(III)-peroxo complex derived directly from dioxygen.

Ryan L Shook1, William A Gunderson, John Greaves

  • 1Department of Chemistry, University of California-Irvine, 1102 Natural Sciences II, Irvine, California 92697-2025, USA.

Journal of the American Chemical Society
|June 24, 2008
PubMed
Summary

Researchers identified a novel peroxomanganese(III) complex (2) by studying dioxygen activation with a manganese(II) complex (1). This reactive intermediate is crucial for understanding metal-catalyzed oxidation reactions.

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Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate
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Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate

Published on: June 18, 2020

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Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts
05:47

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Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate
09:02

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate

Published on: June 18, 2020

Area of Science:

  • Inorganic Chemistry
  • Bioinorganic Chemistry
  • Reaction Mechanisms

Background:

  • Transition metal complexes play a vital role in dioxygen binding and activation.
  • Peroxometal species are key, yet often transient, intermediates in these reactions.
  • Understanding these intermediates is crucial for catalysis and biological processes.

Purpose of the Study:

  • To investigate the interaction of dioxygen with a specific manganese(II) complex (1).
  • To detect and characterize novel reactive intermediates in this process.
  • To explore the reactivity and potential biological relevance of the observed intermediate.

Main Methods:

  • Synthesis and characterization of a manganese(II) complex (1).
  • Reaction with dioxygen (16O2 and 18O2) to form a peroxomanganese(III) complex (2).
  • Spectroscopic analysis including Electron Paramagnetic Resonance (EPR), Fourier Transform Infrared (FTIR), and Electrospray Ionization Mass Spectrometry (ESI-MS).

Main Results:

  • Detection and characterization of a high-spin peroxomanganese(III) complex (2) (S = 2, g = 8.2, D = -2.0(5)).
  • Confirmation of peroxo ligand coordination using FTIR (16O2 vs. 18O2 isotopic shift).
  • Mass spectrometry confirmed the isotopic composition of the intermediate.

Conclusions:

  • A novel, reactive peroxomanganese(III) intermediate (2) was successfully isolated and characterized.
  • The intermediate exhibits reactivity, including oxidative deformylation of aldehydes.
  • The findings offer insights into metal-mediated oxygen activation and potential parallels with biological systems like cytochrome P450.