Related Experiment Video
Updated: Jul 4, 2026

Quantitative Polymerase Chain Reaction (qPCR)-Based Rapid Diagnosis of Helicobacter pylori Infection and Antibiotic Resistance
Published on: July 28, 2023
[Management of Helicobacter pylori infection in primary care in Spain]
Emili Gené1, Jordi Sánchez-Delgado, Xavier Calvet
1Servei d'Urgències, Hospital de Sabadell, Institut Universitari Parc Taulí, Parc Taulí s/n, Sabadell, Barcelona, Spain. 29833egt@comb.es
Objective:
The indications on when and how to diagnose and treat ulcerative disease and Helicobacter pylori infection are reasonably clear. The aim of this study was to evaluate the management of H. pylori infection and access to diagnostic tests in primary care.
Material And Methods:
We performed an observational, cross-sectional study. An anonymous questionnaire was sent to Spanish primary care physicians throughout Spain. Compliance with the major consensus conference recommendations on H. pylori treatment was evaluated.
Results:
The questionnaire was completed by 991 primary care physicians. A total of 87.7% of respondents reported they had indicated eradication therapy at least once during the previous year: 79.9% for duodenal ulcer, 75.3% for gastric ulcer, and 18.3% for gastroesophageal reflux disease. The treatment schedule was correct according to the consensus in 74.7% of the responses. However, 29% prescribed 14-day therapy, which is longer than the recommended duration. Sixty-seven per cent of practitioners maintained continuous or intermittent anti-secretory treatment in asymptomatic ulcerous patients and did not indicate H. pylori eradication therapy. The availability of different tests was as follows: 64.7% of respondents had access to endoscopy, 67.4% to urea breath test, 59.6% to serology, and 11.9% to the H. pylori stool antigen test. There were substantial regional variations in access to diagnostic tests.
Conclusions:
Management of H. pylori infection is reasonably well adapted to consensus recommendations. Nevertheless, there is marked geographic variation and substantial restrictions in access to diagnostic tests, which hampers application of the recommendations.
Related Concept Videos
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Peptic Ulcer
Acid Suppressive Drugs for Peptic Ulcer Disease: Proton Pump Inhibitors
Gastric acid, a potent cocktail of hydrogen and chloride ions, is produced in specialized parietal cells within the...
