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Updated: Jul 4, 2026

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
Published on: June 24, 2015
The electrical coupling confers to a network of interneurons the ability of transmitting excitatory inputs with high
1CNR - Istituto di Biofisica, via G. Moruzzi 1, 56124, Pisa, Italy. angelo.digarbo@pi.ibf.cnr.it
Abstract:
The transmission of excitatory inputs by inhibitory networks of different sizes is investigated by means of numerical simulations. The interneurons are coupled by electrical and/or inhibitory synapses and each of them receives an excitatory pulse at a random time. The pulse times are extracted from a Gaussian distribution and each cell model is subject to an independent noisy current. The results described in this paper suggest that the presence of the electrical coupling promotes the transmission of the excitatory synaptic inputs on a time scale of a few milliseconds.
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