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Forward Genetic Approaches in Chlamydia trachomatis
Published on: October 23, 2013
[Parameters of a reproductive function in males with a history of genital chlamydial infection]
Abstract:
We examined 243 males using polymerase chain reaction (PCR), seeding, spermogram, morphological examination of spermatozoa, electrospermography, enzyme immunoassay (antibodis to chlamydia in blood serum and seminal plasma, blood hormones). Statistics were obtained with parametric and nonparametric methods. A total of 148 patients were divided into three groups. Group 1 (n = 57) consisted of males who had previously had chlamydiasis. Their blood serum and/or seminal plasma contained antichlamydial IgA or IgG. Neither seeding nor PCR detected genital infections. Group 2 consisted of 18 patients infected with C. trachomatis. Control patients (n = 73) had no genital infections, chlamydial antibodies were not detected. Normozoospermia was diagnosed in 28% males with chlamydial infection history, 11% patients infected with chlamydia and 23% controls. Asthenozoospermia was detected in 69, 89 and 73% patients, respectively. Among chlamydial infection convalescents were patients with obstructive azoospermia (2%) which was not found in infected and healthy males.
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